SCHEMBL29851846

SCHEMBL29851846

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)O)C(C)C)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 16/20 0.64
▸ NMBR P28336 2/20 0.64
▸ GLP1R P43220 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bombesin SCHEMBL29353003 0.94 GRPR (0.70) GRPRNMBR
SCHEMBL30783571 0.89 GRPR (0.65) GRPRNMBR
Bombesin SCHEMBL29364598 0.87 GRPR (0.66) GRPRNMBR
SCHEMBL29565297 0.84 GRPR (0.68) GRPRNMBRGLP1R
SCHEMBL31738529 0.84 GRPR (0.62) GRPRNMBRGLP1R
SCHEMBL4344249 0.83 GRPR (0.69) GRPR
SCHEMBL16508339 0.82 GRPR (0.69) GRPR
SCHEMBL19102240 0.82 GRPR (0.69) GRPR
SCHEMBL1413932 0.82 GRPR (0.68) GRPR
SCHEMBL1413933 0.82 GRPR (0.68) GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634474-B1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL EUROPE GMBH (DE) 2026-05-06 — — EP disclosed
WO-2025227105-A1 CLEAVABLE LINKERS WITH TUNABLE HALF-LIVES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-10-30 — — WO disclosed
US-12173063-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer, infections and autoimmune disorders AVENCELL EUROPE GMBH (DE) 2024-12-24 — — US disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD THERAPEUTICS LIMITED (CN) 2024-08-15 — — US disclosed
EP-4313154-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD Therapeutics Limited (HK) 2024-02-07 — — EP disclosed
CN-110678198-B Targeting modules to immune cells expressing universal chimeric antigen receptor and their use in the treatment of cancer, infections and autoimmune disorders 阿文塞勒欧洲有限公司 2024-02-02 — — CN disclosed
CN-117164726-A Targeting module for immune cells expressing universal chimeric antigen receptor and uses thereof 阿文塞勒欧洲有限公司 2023-12-05 — — CN disclosed
US-20230272066-A1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER, INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL THERAPEUTICS, INC. 2023-08-31 — — US disclosed
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders AVENCELL EUROPE GMBH (DE) 2023-01-24 — — US disclosed
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2022-12-22 — — US disclosed
WO-2022212362-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2022-10-06 — — WO disclosed
EP-4037715-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2022-08-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272066-A1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER, INFECTIONS AND AUTOIMMUNE DISORDERS CD74, HAVCR2, CD4 GRPR 695/4885NMBR 385/4885GLP1R 2288/4885
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, MACROD1, MSN GRPR 2596/4885NMBR 1519/4885GLP1R 3793/4885
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders CD74, HAVCR2, CD4 GRPR 703/4885NMBR 376/4885GLP1R 2595/4885
US-12173063-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer, infections and autoimmune disorders CD74, HAVCR2, CD4 GRPR 695/4885NMBR 385/4885GLP1R 2288/4885
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, SSB, DNPEP GRPR 1943/4885NMBR 1747/4885GLP1R 3651/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR GRPR 9/4885NMBR 224/4885GLP1R 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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