Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294478 | 1.00 | CA12 (0.52) | CA12ACMSDCTRCESR1ESR2 | |
| SCHEMBL29852112 | 0.94 | CA12 (0.55) | CA12ACMSDCTRCESR1ESR2 | |
| SCHEMBL23294462 | 0.94 | CA12 (0.55) | CA12ACMSDCTRCESR1ESR2 | |
| SCHEMBL29852146 | 0.93 | CA12 (0.47) | CA12ACMSDCTRCESR1ESR2 | |
| SCHEMBL23294396 | 0.93 | CA12 (0.47) | CA12ACMSDCTRCESR1ESR2 | |
| SCHEMBL23303650 | 0.87 | KMO (0.46) | ACMSDHAO1MAP2K4 | |
| SCHEMBL31246119 | 0.87 | KMO (0.46) | ACMSDHAO1MAP2K4 | |
| SCHEMBL23294375 | 0.86 | MAP2K4 (0.45) | ALPLHAO1MAPK10MAP2K4 | |
| SCHEMBL23294477 | 0.86 | MAP2K4 (0.45) | ALPLHAO1MAPK10MAP2K4 | |
| SCHEMBL23294619 | 0.86 | MAP2K4 (0.45) | CA12CTRCALPLHAO1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-B | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |