Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10666393 | 0.98 | GAA (0.50) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL29052430 | 0.86 | GAA (0.42) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL32683914 | 0.86 | GAA (0.41) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL17007815 | 0.83 | GAA (0.49) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL1639886 | 0.83 | GAA (0.51) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL29052434 | 0.82 | GAA (0.40) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL1224892 | 0.81 | GAA (0.50) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL27708829 | 0.81 | GAA (0.50) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL976056 | 0.81 | GAA (0.50) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL6642192 | 0.80 | GAA (0.38) | GAASMN1; SMN2RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480007-B | Synthetic method of 1,3-dimethyl-1H-pyrazole-4-carboxylic acid | 宿迁市科莱博生物化学有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-110372594-B | Synthesis method of 1, 3-dimethyl-1H-pyrazole-4-formic acid | 苏州汉德创宏生化科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-114014809-A | Synthetic method of 1, 3-dimethyl-1H-pyrazole-4-carboxylic acid | 宁夏常晟药业有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-112480007-A | Synthetic method of 1, 3-dimethyl-1H-pyrazole-4-carboxylic acid | 宿迁市科莱博生物化学有限公司 | 2021-03-12 | — | — | CN | claimed |
| EP-2755963-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-10-30 | — | — | EP | claimed |
| CN-110372594-A | The synthetic method of 1,3- dimethyl -1H- pyrazoles -4- formic acid | 苏州汉德创宏生化科技有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-108117520-A | A kind of 1,3- dimethyl -1H- pyrazoles -4- amide derivatives and preparation method and application | 浙江工业大学 | 2018-06-05 | — | — | CN | claimed |
| EP-2507230-B1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | claimed |
| CN-107033084-A | A kind of acyl urea compound for containing 1,3 dimethyl 1H pyrrazole structures and its preparation method and application | 浙江工业大学 | 2017-08-11 | — | — | CN | claimed |
| CN-107033082-A | A kind of acyl thiourea compound for containing 1,3 dimethyl 1H pyrrazole structures and its preparation method and application | 浙江工业大学 | 2017-08-11 | — | — | CN | claimed |
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | claimed |
| EP-2185512-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-05-19 | — | — | EP | claimed |
| US-20100016401-A1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | Actelion Phamaceuticals Ltd. (CH) | 2010-01-21 | — | — | US | claimed |
| CN-101568536-A | 2-aza-bicyclo[3.1.0]hexane derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-28 | — | — | CN | claimed |
| EP-2094690-A2 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2009-09-02 | — | — | EP | claimed |
| CN-101522618-A | 3-aza-bicyclo[3.1.0]hexane derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | claimed |
| EP-2079690-A2 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-07-22 | — | — | EP | claimed |
| WO-2009016560-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-05 | — | — | WO | claimed |
| WO-2008081399-A2 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-10 | — | — | WO | claimed |
| WO-2008038251-A2 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-04-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016401-A1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | HCRTR1, HCRTR2, CNR1 | GAA 3717/4885SMN1; SMN2 3816/4885RAB9A 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.