Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 8/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318640 | 0.84 | CYP4F2 (0.55) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL10375085 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL27224530 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL16318580 | 0.81 | CYP4F2 (0.56) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL21476229 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL20103289 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL10375080 | 0.80 | SYK (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL4863083 | 0.80 | ALDH1A1 (0.52) | CYP4F2CYP4A11KDM4EALDH1A1KDM6B | |
| SCHEMBL7039459 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL27224523 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11SYKPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059933-A1 | AZABENZIMIDAZOLE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2022-09-21 | — | — | EP | disclosed |
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | disclosed |