Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218175 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL23218217 | 0.90 | ALDH1A1 (0.40) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL29853053 | 0.90 | ALDH1A1 (0.40) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL29853241 | 0.90 | KMT2A (0.41) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL23218361 | 0.90 | KMT2A (0.41) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL23219259 | 0.88 | TBXAS1 (0.41) | KMT2AMEN1TBXAS1MAPTTSHR | |
| SCHEMBL29853250 | 0.88 | TBXAS1 (0.41) | KMT2AMEN1TBXAS1MAPTTSHR | |
| SCHEMBL29852506 | 0.87 | TSHR (0.40) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL23218789 | 0.87 | TSHR (0.40) | KMT2AALDH1A1HPGDHTTMEN1 | |
| SCHEMBL23218330 | 0.87 | TBXAS1 (0.40) | KMT2ACYP2C9CYP2C19TBXAS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |