Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218680 | 1.00 | THRB (0.41) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL29853198 | 0.90 | ALOX5 (0.38) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL29593139 | 0.90 | MEN1 (0.37) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL23218492 | 0.90 | MEN1 (0.37) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL23218199 | 0.90 | ALOX5 (0.38) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL23218128 | 0.89 | MAOB (0.40) | MEN1POLBGAAKMT2AMAPT | |
| SCHEMBL29852717 | 0.89 | MAPT (0.40) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL23218697 | 0.89 | MAPT (0.40) | THRBMEN1POLBGAAKMT2A | |
| SCHEMBL29852861 | 0.89 | MAOB (0.40) | MEN1POLBGAAKMT2AMAPT | |
| SCHEMBL23218939 | 0.89 | NPC1 (0.36) | THRBMEN1POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |