SCHEMBL2985452

SCHEMBL2985452

CCN(C)/C=N\c1cc(C)c(Oc2cccc(CC(C)(C)C)c2)cc1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2985454 1.00 RIPK1 (0.30) RIPK1
SCHEMBL12710246 1.00 RIPK1 (0.30) RIPK1
SCHEMBL4430664 0.87
SCHEMBL4427198 0.87
SCHEMBL2988678 0.87 NR1H2 (0.36)
SCHEMBL2988680 0.87 NR1H2 (0.36)
SCHEMBL2985567 0.85
SCHEMBL4430577 0.85 CYP4F2 (0.36)
SCHEMBL2988752 0.85
SCHEMBL12710247 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2136628-B1 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER IP GMBH (DE) 2015-07-01 EP claimed
US-8394991-B2 Phenoxy substituted phenylamidine derivatives and their use as fungicides BAYER CROPSCIENCE AG (DE) 2013-03-12 US claimed
US-20120122678-A1 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-05-17 US claimed
US-20100167926-A1 3-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-07-01 US claimed
EP-1969932-A1 Phenoxy substituted phenylamidine derivatives and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed
EP-2136628-B1 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER IP GMBH (DE) 2015-07-01 EP disclosed
US-8394991-B2 Phenoxy substituted phenylamidine derivatives and their use as fungicides BAYER CROPSCIENCE AG (DE) 2013-03-12 US disclosed
US-20120122678-A1 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-05-17 US disclosed
US-20100167926-A1 3-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
EP-2136628-A2 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES Bayer CropScience AG (DE) 2009-12-30 EP disclosed
WO-2008110280-A2 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO disclosed
EP-1969932-A1 Phenoxy substituted phenylamidine derivatives and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122678-A1 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES PAH, DDT, PFAS RIPK1 4516/4885
US-20100167926-A1 3-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES DDT, PAH, TH RIPK1 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.