Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851626 | 0.82 | PDE1C (0.37) | SSTR4 | |
| SCHEMBL25285831 | 0.81 | HPGDS (0.42) | SSTR4HPGDSCHEK1 | |
| SCHEMBL23851633 | 0.80 | AURKA (0.36) | SSTR4CDK2 | |
| SCHEMBL5880422 | 0.78 | AURKA (0.41) | SSTR4CCNA2CDK2 | |
| SCHEMBL31153589 | 0.75 | SSTR4 (0.34) | SSTR4 | |
| SCHEMBL17895133 | 0.74 | HTR3A (0.36) | CHRNB2CHRNA4HPGDSCHRNB4CHRNA3 | |
| SCHEMBL31153530 | 0.73 | PDE1C (0.36) | SSTR4 | |
| SCHEMBL21404552 | 0.73 | MAPK8 (0.33) | SSTR4 | |
| SCHEMBL21404470 | 0.73 | TNK2 (0.35) | SSTR4 | |
| SCHEMBL7547733 | 0.71 | KDM4E (0.44) | HPGDSHTR2CCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433190-B | Preparation method and application of irreversible heterocyclic compound FGFR inhibitor | 药雅科技(上海)有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2022166469-A1 | FGFR KINASE INHIBITOR AND USE THEREOF | 药雅科技(上海)有限公司 | 2022-08-11 | — | — | WO | disclosed |