SCHEMBL29856223

SCHEMBL29856223

Oc1cc(Cl)cc2nc3ccccc3nc12

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
ALDH1A1 P00352 3/20 0.57
GAA P10253 1/20 0.57
RAB9A P51151 1/20 0.57
KMT2A Q03164 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
MYC P01106 1/20 0.55
MAX P61244 1/20 0.55
NQO2 P16083 8/20 0.53
ACHE P22303 1/20 0.47
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 2/20 0.38
HCRTR1 O43613 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29856269 0.81 NQO2 (0.50) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856225 0.81 NQO2 (0.50) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856246 0.81 NQO2 (0.42) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856293 0.81 NQO2 (0.50) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856318 0.81 NQO2 (0.42) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856813 0.81 KDM4E (0.50) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29856316 0.80 ALDH1A1 (0.46) MAPTALDH1A1KMT2AMYCMAX
SCHEMBL8764691 0.77 MAPT (0.57) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL23612607 0.77 NQO2 (0.72) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL20475366 0.77 NQO2 (0.72) MAPTALDH1A1GAARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US disclosed
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS ROS1, NOX4, NOX5 MAPT 3143/4885ALDH1A1 348/4885GAA 2614/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 MAPT 3143/4885ALDH1A1 348/4885GAA 2614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.