Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554404 | 0.86 | HPGD (0.47) | HSD17B10HPGDRAB9ANPC1TP53 | |
| SCHEMBL3932458 | 0.84 | NNMT (0.54) | HSD17B10HPGDRAB9ANPC1KMT2A | |
| SCHEMBL26789819 | 0.84 | HTT (0.46) | HSD17B10HPGDRAB9ANPC1TP53 | |
| SCHEMBL19780075 | 0.83 | NNMT (0.53) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL26789530 | 0.81 | RAB9A (0.54) | HSD17B10HPGDRAB9ANPC1TP53 | |
| SCHEMBL31554490 | 0.78 | RAB9A (0.40) | HSD17B10HPGDRAB9ANPC1TP53 | |
| SCHEMBL26789805 | 0.78 | RAB9A (0.56) | HSD17B10HPGDRAB9ANPC1TP53 | |
| SCHEMBL7681674 | 0.77 | NNMT (0.47) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29713519 | 0.77 | NNMT (0.47) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2253522 | 0.76 | NNMT (0.66) | KMT2AMEN1ALDH1A1NNMTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |