Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856136 | 0.86 | SLC22A12 (0.47) | SLC22A12SLC22A6ABCG2ELANEEGFR | |
| SCHEMBL29856238 | 0.83 | SLC22A12 (0.43) | SLC22A12ELANEEGFRSRCRORC | |
| SCHEMBL29856265 | 0.80 | SLC22A12 (0.47) | SLC22A12SLC22A6ABCG2ELANEEGFR | |
| SCHEMBL29856387 | 0.77 | SLC22A12 (0.46) | SLC22A12 | |
| SCHEMBL29856299 | 0.73 | SMN1; SMN2 (0.49) | EGFRALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL28560524 | 0.73 | FEN1 (0.46) | ELANEEGFRSRCKDM4EMEN1 | |
| SCHEMBL29856235 | 0.70 | SLC22A12 (0.39) | SLC22A12RORCCYP3A4 | |
| SCHEMBL29856141 | 0.68 | SLC22A12 (0.39) | SLC22A12SLC22A6ABCG2MEN1NR1I2 | |
| SCHEMBL21979475 | 0.67 | EGFR (0.50) | ELANEEGFRSRCTNKSRORC | |
| SCHEMBL29302071 | 0.66 | FEN1 (0.43) | SLC22A12ELANEEGFRSRCTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |