Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856282 | 0.80 | SLC22A12 (0.48) | SLC22A12SLC22A6ABCG2ELANEEGFR | |
| SCHEMBL29856218 | 0.78 | SLC22A12 (0.44) | SLC22A12ELANE | |
| SCHEMBL17846559 | 0.74 | ELANE (0.41) | ELANEEGFRSRCKDM4EFEN1 | |
| SCHEMBL29856150 | 0.74 | SLC22A12 (0.42) | SLC22A12ELANE | |
| SCHEMBL29856402 | 0.72 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL29856491 | 0.72 | SLC22A12 (0.38) | SLC22A12RORCCYP3A4 | |
| SCHEMBL29856251 | 0.70 | ELANE (0.41) | SLC22A12ELANEMAPTCYP2C9 | |
| SCHEMBL14739634 | 0.66 | PTGDR2 (0.39) | TNKSKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL14739637 | 0.66 | PTGDR2 (0.39) | TNKSKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL29856136 | 0.66 | SLC22A12 (0.47) | SLC22A12SLC22A6ABCG2ELANEEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |