Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357467 | 1.00 | DAO (0.49) | DAOMAPTSNCAHRH4DHFR | |
| SCHEMBL13656963 | 0.86 | DAO (0.46) | DAOMAPTSNCAHRH4CLK2 | |
| SCHEMBL4269626 | 0.86 | DAO (0.50) | DAOMAPTSNCAHRH4CLK2 | |
| SCHEMBL14327807 | 0.85 | DAO (0.49) | DAOMAPTSNCAHRH4DHFR | |
| Hydrochloric Acid SCHEMBL4271746 | 0.84 | DAO (0.45) | DAOMAPTSNCAHRH4CLK2 | |
| SCHEMBL4271962 | 0.83 | DAO (0.47) | DAOMAPTSNCAHRH4CLK2 | |
| SCHEMBL23934135 | 0.80 | DAO (0.42) | DAOMAPTSNCAHRH4CLK2 | |
| SCHEMBL4271774 | 0.79 | DAO (0.44) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL22016193 | 0.76 | DAO (0.59) | DAOMAPTSNCAHRH4GSK3B | |
| SCHEMBL4041624 | 0.76 | KDM4E (0.41) | DAOMAPTSNCAHRH4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |