Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 11/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.36 |
| ▸ | PGR | P06401 | 6/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934146 | 0.88 | DAO (0.42) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL29856283 | 0.80 | DAO (0.49) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL3357467 | 0.80 | DAO (0.49) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL4269626 | 0.78 | DAO (0.50) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL13656963 | 0.78 | DAO (0.46) | DAOMAPTSNCAHRH4NR3C1 | |
| Hydrochloric Acid SCHEMBL4271746 | 0.76 | DAO (0.45) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL4271962 | 0.75 | DAO (0.47) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL4271774 | 0.75 | DAO (0.44) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL23487158 | 0.72 | DAO (0.44) | DAOMAPTSNCAHRH4NR3C1 | |
| SCHEMBL21672768 | 0.72 | NR3C1 (0.35) | DAOMAPTSNCANR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323941-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | THE UNIVERSITY OF KANSAS | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323941-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | SLC6A3, DRD3, CHRM2 | DAO 1368/4885MAPT 470/4885SNCA 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.