SCHEMBL29856433

SCHEMBL29856433

CNc1nc(Br)cn2c(CO)cnc12

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TTK P33981 1/20 0.35
IKBKB O14920 5/20 0.34
FLT3 P36888 2/20 0.32
YTHDC1 Q96MU7 1/20 0.30
CHUK O15111 2/20 0.30
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319030 0.80 IKBKB (0.43) TTKIKBKBFLT3YTHDC1CHUK
SCHEMBL14432369 0.78 IKBKB (0.41) TTKIKBKBFLT3YTHDC1CHUK
SCHEMBL19748170 0.77 IKBKB (0.36) TTKIKBKBFLT3YTHDC1CHUK
SCHEMBL25394938 0.75 TTK (0.36) TTKIKBKBFLT3YTHDC1CHUK
SCHEMBL25395707 0.72 KDM4E (0.42) TTK
SCHEMBL13157185 0.68 TTK (0.44) TTKFLT3
SCHEMBL15722490 0.67 BRD4 (0.45)
SCHEMBL7324280 0.67 TTK (0.38) TTKIKBKBCHUKLRRK2
SCHEMBL31285537 0.66 IKBKB (0.46) IKBKBFLT3YTHDC1CHUK
SCHEMBL31083043 0.65 MET (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022189503-A1 AN OPTOGENETIC VOLTAGE CLAMP (OVC) AND USES THEREOF Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) 2022-09-15 WO disclosed
EP-4056681-A1 AN OPTOGENETIC VOLTAGE CLAMP (OVC) AND USES THEREOF Johann Wolfgang Goethe-Universität Frankfurt (DE) 2022-09-14 EP disclosed