Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ascorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
| ▸ | TST | Q16762 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | MANBA | O00462 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ascorbic Acid SCHEMBL5968922 | 0.97 | MAPT (0.83) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL10535642 | 0.95 | MAPT (0.76) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL408448 | 0.94 | MAPT (0.78) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL21372601 | 0.92 | MAPT (0.81) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL21372602 | 0.92 | LMNA (0.81) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL21372605 | 0.92 | MAPT (0.81) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL21114349 | 0.91 | MAPT (1.00) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL18678 | 0.91 | MAPT (1.00) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL2564750 | 0.91 | MAPT (1.00) | MAPTLMNAL3MBTL1HSPD1HSPE1 | |
| Ascorbic Acid SCHEMBL786 | 0.91 | MAPT (1.00) | MAPTLMNAL3MBTL1HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115154358-A | Permanent wave agent for reducing hair damage and hot wave method thereof | 湘潭湘莱生物科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-115154358-A | Permanent wave agent for reducing hair damage and hot wave method thereof | 湘潭湘莱生物科技有限公司 | 2022-10-11 | — | — | CN | disclosed |