Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26916550 | 1.00 | KMT2A (0.44) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL26916976 | 0.78 | PDGFRB (0.44) | USP7ALDH1A1CHEK1CCNA2CDK2 | |
| SCHEMBL17255919 | 0.75 | KMT2A (0.65) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL17203430 | 0.73 | KMT2A (0.44) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL27742561 | 0.73 | RAB9A (0.50) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL26916746 | 0.70 | FYN (0.53) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL29582823 | 0.70 | FYN (0.53) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL17203507 | 0.70 | PIK3CD (0.49) | KMT2AHTTMEN1ALDH1A1NPC1 | |
| SCHEMBL16432199 | 0.69 | KMT2A (0.52) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL12489163 | 0.68 | USP7 (0.53) | KMT2AHTTMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288437-A1 | MAP4K1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167627-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | WO | disclosed |