Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26917296 | 1.00 | POLB (0.50) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL9955393 | 0.81 | GAA (0.43) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL16007066 | 0.78 | POLB (0.39) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL20680345 | 0.78 | ALDH1A1 (0.41) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL21761104 | 0.78 | DAO (0.40) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL31238875 | 0.78 | MAOB (0.43) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL26130944 | 0.78 | MAOB (0.43) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL10636018 | 0.77 | POLB (0.61) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL17927636 | 0.77 | HSD17B10 (0.41) | POLBSMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL29858070 | 0.76 | MEN1 (0.46) | POLBSMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288437-A1 | MAP4K1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167627-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | WO | disclosed |