Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26917296 | 0.81 | POLB (0.50) | MAPTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL29858085 | 0.81 | POLB (0.50) | MAPTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL31429909 | 0.81 | GAA (0.43) | GAAMAPTPKMPOLBHSD17B10 | |
| SCHEMBL31238875 | 0.78 | MAOB (0.43) | MAPTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL26130944 | 0.78 | MAOB (0.43) | MAPTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20680345 | 0.78 | ALDH1A1 (0.41) | GAAMAPTPKMPOLBHSD17B10 | |
| SCHEMBL16007066 | 0.78 | POLB (0.39) | GAAMAPTPKMPOLBHSD17B10 | |
| SCHEMBL21761104 | 0.78 | DAO (0.40) | GAAMAPTPKMPOLBHSD17B10 | |
| SCHEMBL17927636 | 0.77 | HSD17B10 (0.41) | GAAMAPTPKMPOLBHSD17B10 | |
| SCHEMBL29858070 | 0.76 | MEN1 (0.46) | MAPTPKMPOLBHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |