Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL3645093 | 0.91 | THRA (0.59) | THRATHRBPPARAPPARGALOX5 | |
| Methacrylic Acid SCHEMBL299931 | 0.90 | THRA (0.55) | THRATHRBPPARAPPARGALOX5 | |
| Propylene Glycol SCHEMBL9425194 | 0.89 | ALOX5 (0.51) | THRATHRBPPARAPPARGALOX5 | |
| Acrylic Acid SCHEMBL299562 | 0.88 | THRA (0.60) | THRATHRBPPARAPPARGALOX5 | |
| SCHEMBL27568869 | 0.82 | THRA (0.55) | THRATHRBPPARAPPARGALOX5 | |
| Glycerin SCHEMBL10710972 | 0.81 | THRA (0.51) | THRATHRBPPARAPPARGALOX5 | |
| Propylene Glycol SCHEMBL28311713 | 0.79 | ALOX5 (0.50) | THRATHRBPPARAPPARGALOX5 | |
| Propylene Glycol SCHEMBL27406207 | 0.79 | ALOX5 (0.61) | THRATHRBPPARAALOX5PTGS2 | |
| Formaldehyde SCHEMBL2768503 | 0.79 | THRA (0.61) | THRATHRBPPARAPPARGALOX5 | |
| Acrylic Acid SCHEMBL6226537 | 0.78 | THRA (0.71) | THRATHRBPPARAPPARGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486940-B2 | Radiation curable resin systems for composite materials and methods for use thereof | AUTOLIV ASP, INC. (US) | 2016-11-08 | — | — | US | claimed |
| EP-0780712-B1 | Peelable bonded ribbon matrix material; optical fiber bonded ribbon arrays containing the same; and process for preparing said optical fiber bonded ribbon arrays | HEXION SPECIALTY CHEMICALS INC (US) | 2006-09-06 | — | — | EP | claimed |
| US-6498883-B1 | Optical fiber ribbon with pigmented matrix material and processes for making same | BORDEN CHEMICAL, INC. | 2002-12-24 | — | — | US | claimed |
| WO-2002081396-A1 | OPTICAL FIBER RIBBON WITH PIGMENTED MATRIX, AND METHODS FOR MAKING AND USING SAME | BORDEN CHEMICAL, INC. (US) | 2002-10-17 | — | — | WO | claimed |
| US-5908873-A | Peelable bonded ribbon matrix material; optical fiber bonded ribbon arrays containing same; and process for preparing said optical fiber bonded ribbon arrays | BORDEN CHEMICALS, INC. (US) | 1999-06-01 | — | — | US | claimed |
| EP-0780712-A2 | Peelable bonded ribbon matrix material; optical fiber bonded ribbon arrays containing same; and process for preparing said optical fiber bonded ribbon arrays | BORDEN CHEMICAL, INC. (US) | 1997-06-25 | — | — | EP | claimed |
| US-11656423-B2 | Colored ribbon with discrete color layers | CORNING RESEARCH & DEVELOPMENT CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-11391902-B2 | Optical ribbon with printing between opaque primary layer and colored secondary layer | CORNING RESEARCH & DEVELOPMENT CORPORATION (US) | 2022-07-19 | — | — | US | disclosed |
| US-20220050256-A1 | COLORED RIBBON WITH DISCRETE COLOR LAYERS | CORNING RESEARCH & DEVELOPMENT CORPORATION | 2022-02-17 | — | — | US | disclosed |
| EP-3948380-A1 | COLORED RIBBON WITH DISCRETE COLOR LAYERS | Corning Research & Development Corporation (US) | 2022-02-09 | — | — | EP | disclosed |
| US-11169348-B2 | Colored ribbon with discrete color layers | CORNING RESEARCH & DEVELOPMENT CORPORATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-20210165180-A1 | OPTICAL RIBBON WITH PRINTING BETWEEN OPAQUE PRIMARY LAYER AND COLORED SECONDARY LAYER | CORNING RESEARCH & DEVELOPMENT CORPORATION | 2021-06-03 | — | — | US | disclosed |
| WO-2020197709-A1 | COLORED RIBBON WITH DISCRETE COLOR LAYERS | CORNING RESEARCH & DEVELOPMENT CORPORATION (US) | 2020-10-01 | — | — | WO | disclosed |
| US-5538791-A | BASED ON A POLYETHER POLYOL-BASED REACTIVELY TERMINATED ALIPHATIC URETHANE OLIGOMER | BORDEN, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5536529-A | Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith | BORDEN, INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5527835-A | CURABLE ACRYLATED POLYETHERURETHANE WITH ACRYLATE MONOMERS, SILANE COUPLER AND PHOTOINITIATOR | BORDEN, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5352712-A | Modified polyurethane | BORDEN, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0566801-A2 | Organic solvent and water resistant, thermally, oxidatively and hydrolytically stable radiation-curable coatings for optical fibers, optical fibers coated therewith and processes for making same | BORDEN, INC. (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0565798-A1 | Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith | BORDEN, INC. (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5146531-A | Acrylated polyurethane | BORDEN, INC. (US) | 1992-09-08 | — | — | US | disclosed |