Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20836154 | 1.00 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL19631362 | 1.00 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL19631370 | 0.89 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL20956542 | 0.89 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL25613714 | 0.89 | DHODH (0.80) | DHODHMEN1KMT2AMAPK1 | |
| SCHEMBL29859659 | 0.89 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL19631470 | 0.86 | DHODH (1.00) | DHODH | |
| SCHEMBL25613978 | 0.84 | DHODH (0.73) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL25614126 | 0.83 | DHODH (0.71) | DHODHMEN1KMT2AMAPK1RARA | |
| SCHEMBL24142109 | 0.78 | DHODH (0.64) | DHODHMEN1KMT2AMAPK1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107382902-B | Thiazole derivative and application thereof | 华东理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |