Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391527 | 0.80 | DHODH (0.64) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL20836154 | 0.78 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL19631362 | 0.78 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL29859288 | 0.78 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL21391548 | 0.78 | DHODH (0.64) | DHODHMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20956542 | 0.75 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL29859659 | 0.75 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL19631370 | 0.75 | DHODH (1.00) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL25613978 | 0.74 | DHODH (0.73) | DHODHMEN1KMT2AMAPK1LMNA | |
| SCHEMBL25613714 | 0.73 | DHODH (0.80) | DHODHMEN1KMT2AMAPK1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |