Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989544 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL19989477 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL19989476 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL29859453 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL29498503 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL19989453 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL19994841 | 0.81 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL2372122 | 0.79 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL19989269 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBGAATSHR | |
| SCHEMBL29498556 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715608-B | Indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-08-05 | — | — | CN | disclosed |