Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989476 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL19989477 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL2372122 | 0.89 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL29859404 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL19989544 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL1727236 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL848293 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL29498481 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL19994841 | 0.82 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2POLBGAATDP1 | |
| SCHEMBL19989503 | 0.80 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715608-B | Indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-08-05 | — | — | CN | disclosed |