SCHEMBL29859543

SCHEMBL29859543

CCc1ccc2oc(-c3ccc(-c4nc5cc(CC)ccc5o4)s3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.61
▸ SMN1; SMN2 Q16637 7/20 0.61
▸ TP53 P04637 7/20 0.61
▸ RAB9A P51151 6/20 0.61
▸ MEN1 O00255 5/20 0.61
▸ NPC1 O15118 5/20 0.61
▸ ALDH1A1 P00352 5/20 0.61
▸ KMT2A Q03164 5/20 0.61
▸ KDM4E B2RXH2 4/20 0.61
▸ HSD17B10 Q99714 4/20 0.61
▸ HPGD P15428 3/20 0.61
▸ NFKB1 P19838 1/20 0.61
▸ NFKB2 Q00653 1/20 0.61
▸ RELA Q04206 1/20 0.61
▸ GAA P10253 3/20 0.54
▸ ALOX15 P16050 2/20 0.54
▸ TDP1 Q9NUW8 2/20 0.54
▸ HTT P42858 1/20 0.54
▸ TSHR P16473 2/20 0.52
▸ POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23630613 1.00 MAPT (0.61) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL23630626 0.93 RAB9A (0.54) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL29859412 0.93 RAB9A (0.54) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL23630624 0.89 MAPT (0.54) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL29859231 0.89 MAPT (0.54) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL12304282 0.88 RAB9A (0.47) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL23642857 0.86 MAPT (0.48) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL30129872 0.85 RAB9A (0.46) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL13866097 0.85 RAB9A (0.46) MAPTSMN1; SMN2TP53RAB9AMEN1
SCHEMBL28823008 0.82 MAPT (0.64) MAPTSMN1; SMN2TP53RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317992-B Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2025-03-18 — — CN claimed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 — — CN claimed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 — — CN claimed
CN-120077076-A Composition and method for producing the same 默克专利有限公司 2025-05-30 — — CN disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 — — CN disclosed
CN-116848170-A Photoactive bulk polymerized polycycloolefin compositions as optical materials that are shelf-life stable for extended periods of time 普罗米鲁斯有限责任公司 2023-10-03 — — CN disclosed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 — — CN disclosed
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 — — CN disclosed
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