SCHEMBL23630626

SCHEMBL23630626

CCc1ccc2oc(-c3ccc(-c4nc5cc(C)ccc5o4)s3)nc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 13/20 0.54
▸ ALDH1A1 P00352 12/20 0.54
▸ SMN1; SMN2 Q16637 11/20 0.54
▸ NPC1 O15118 11/20 0.54
▸ KDM4E B2RXH2 11/20 0.54
▸ HPGD P15428 10/20 0.54
▸ TP53 P04637 9/20 0.54
▸ HSD17B10 Q99714 9/20 0.54
▸ MAPT P10636 7/20 0.54
▸ MEN1 O00255 5/20 0.54
▸ KMT2A Q03164 5/20 0.54
▸ NFKB1 P19838 4/20 0.54
▸ NFKB2 Q00653 4/20 0.54
▸ RELA Q04206 4/20 0.54
▸ CASP3 P42574 5/20 0.50
▸ SENP7 Q9BQF6 5/20 0.50
▸ SENP6 Q9GZR1 5/20 0.50
▸ SENP8 Q96LD8 4/20 0.50
▸ TDP1 Q9NUW8 3/20 0.50
▸ GAA P10253 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859412 1.00 RAB9A (0.54) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL29859543 0.93 MAPT (0.61) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL23630613 0.93 MAPT (0.61) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL31239357 0.89 KDM4E (0.65) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL318302 0.89 KDM4E (0.65) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL29859231 0.83 MAPT (0.54) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL23630624 0.83 MAPT (0.54) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL13928214 0.83 NPC1 (0.58) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL12304282 0.81 RAB9A (0.47) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL23642857 0.80 MAPT (0.48) RAB9AALDH1A1SMN1; SMN2NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 — — EP claimed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 — — CN claimed
EP-4087889-B1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS LLC (US) 2024-03-06 — — EP claimed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 — — CN claimed
WO-2023097092-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 — — WO claimed
EP-4087889-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF Promerus, LLC (US) 2022-11-16 — — EP claimed
WO-2021142402-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS, LLC (US) 2021-07-15 — — WO claimed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 — — EP disclosed
US-12037431-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS, LLC (US) 2024-07-16 — — US disclosed
US-12037431-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS, LLC (US) 2024-07-16 — — US disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 — — CN disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 — — WO disclosed
EP-4087889-B1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS LLC (US) 2024-03-06 — — EP disclosed
US-20230167256-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 — — US disclosed
US-20230167256-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 — — US disclosed
US-11535702-B2 Long shelf life stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2022-12-27 — — US disclosed
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 — — CN disclosed
WO-2022169801-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2022-08-11 — — WO disclosed
US-20220235161-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS, LLC (US) 2022-07-28 — — US disclosed
US-20210221931-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS, LLC (US) 2021-07-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037431-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof RRP15, PPOX, NONO RAB9A 2324/4885ALDH1A1 2219/4885SMN1; SMN2 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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