Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592571 | 0.89 | HSD17B10 (0.50) | HSD17B10AKT1CHEK1MAPTMAP3K5 | |
| SCHEMBL30592552 | 0.86 | HSD17B10 (0.47) | HSD17B10AKT1CHEK1MAPTKMT2A | |
| SCHEMBL30592547 | 0.86 | HSD17B10 (0.47) | HSD17B10AKT1CHEK1MAPTKMT2A | |
| SCHEMBL29859618 | 0.80 | HSD17B10 (0.56) | HSD17B10AKT1CHEK1MAPTKMT2A | |
| SCHEMBL30592586 | 0.78 | HSD17B10 (0.47) | HSD17B10AKT1CHEK1MAPTLMNA | |
| SCHEMBL3382220 | 0.73 | HSD17B10 (0.66) | HSD17B10AKT1CHEK1MAPTKMT2A | |
| SCHEMBL18341944 | 0.71 | HSD17B10 (0.51) | HSD17B10AKT1CHEK1MAPTLMNA | |
| SCHEMBL31716653 | 0.71 | HSD17B10 (0.63) | HSD17B10AKT1CHEK1MAPTLMNA | |
| SCHEMBL18341894 | 0.69 | HSD17B10 (0.55) | HSD17B10MAPTKMT2AMEN1LMNA | |
| SCHEMBL25780379 | 0.69 | HSD17B10 (0.49) | HSD17B10AKT1CHEK1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888127-A | Tri-fused ring HPK1 inhibitor and application thereof | 轩竹生物科技股份有限公司 | 2023-10-13 | — | — | CN | disclosed |