Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 14/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MITF | O75030 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 19/20 | 0.70 |
| ▸ | RAB9A | P51151 | 19/20 | 0.70 |
| ▸ | GAA | P10253 | 12/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.70 |
| ▸ | RELA | Q04206 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 7/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.70 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.70 |
| ▸ | NSD2 | O96028 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915293 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL26935144 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL26915313 | 0.84 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL26935005 | 0.84 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL12235860 | 0.83 | NPC1 (0.78) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL13187328 | 0.83 | RAB9A (0.76) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL12258440 | 0.83 | NPC1 (0.76) | MAPTSMN1; SMN2ALDH1A1MITFNPC1 | |
| SCHEMBL12581545 | 0.82 | NPC1 (0.75) | MAPTSMN1; SMN2ALDH1A1MITFHPGD | |
| SCHEMBL12258490 | 0.82 | NOX1 (0.73) | MAPTSMN1; SMN2ALDH1A1MITFNPC1 | |
| SCHEMBL12258152 | 0.82 | NPC1 (1.00) | MAPTSMN1; SMN2ALDH1A1MITFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117042759-A | IL-31 production inhibitor and pharmaceutical composition containing the same | 国立大学法人九州大学 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022168962-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 国立大学法人九州大学 | 2022-08-11 | — | — | WO | disclosed |