SCHEMBL29860072

SCHEMBL29860072

CCN1CCc2cc(S(=O)(=O)O)ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
TSHR P16473 2/20 0.46
NOTUM Q6P988 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
GLA P06280 1/20 0.45
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
ADRB2 P07550 2/20 0.43
ADRB1 P08588 2/20 0.43
ADRB3 P13945 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14266678 0.88 ROCK1 (0.49) POLBTSHRNOTUMALDH1A1HPGD
SCHEMBL3112781 0.86 NOTUM (0.45) POLBTSHRNOTUMALDH1A1HPGD
SCHEMBL14058837 0.86 CA1 (0.52) POLBTSHRNOTUMALDH1A1KDM4E
SCHEMBL31130019 0.86 NOTUM (0.45) POLBTSHRNOTUMALDH1A1HPGD
SCHEMBL9336666 0.80 POLB (0.43) POLBTSHRNOTUMALDH1A1HPGD
SCHEMBL3227479 0.79 CA12 (0.47) POLBTSHRNOTUMALDH1A1HPGD
SCHEMBL30049294 0.77 DRD2 (0.49) NOTUMALDH1A1
SCHEMBL4808175 0.76 NOTUM (0.67) NOTUMALDH1A1LMNASMN1; SMN2TP53
SCHEMBL19777847 0.76 POLB (0.55) POLBTSHRALDH1A1HPGDKDM4E
SCHEMBL20178650 0.75 ACHE (0.54) POLBNOTUMALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120019162-A Spatially resolved surface capture of nucleic acids 元素生物科学公司 2025-05-16 CN disclosed
CN-120019161-A Compositions and methods for preparing nucleic acid nanostructures using compacted oligonucleotides 元素生物科学公司 2025-05-16 CN disclosed
CN-119923478-A PCR-free library preparation using double-stranded splint adaptors and methods of use 元素生物科学公司 2025-05-02 CN disclosed
CN-119698483-A Compositions and methods for reducing base recognition errors by removing deaminated nucleotides from a nucleic acid library 元素生物科学公司 2025-03-25 CN disclosed
CN-119698470-A Has improved thermal stability is an engineered polymerase of (a) 元素生物科学公司 2025-03-25 CN disclosed
CN-119654422-A Adaptor trimming and determination in next generation sequencing data analysis 元素生物科学公司 2025-03-18 CN disclosed
CN-119630954-A Image registration in preliminary analysis 元素生物科学公司 2025-03-14 CN disclosed
CN-119585800-A Back and forth correction of base interpretation in next generation sequencing 元素生物科学公司 2025-03-07 CN disclosed
CN-119487205-A Single chain link clamp chain and method of use 元素生物科学公司 2025-02-18 CN disclosed
CN-119173640-A Double stranded splint adaptors and methods of use 元素生物科学公司 2024-12-20 CN disclosed
US-20240418711-A1 NEW NANOPARTICLES FOR USE IN THE DETECTION OF TARGET BIOMOLECULES APLEX BIO AB (SE) 2024-12-19 US disclosed
CN-119032166-A Engineered polymerases with reduced sequence-specific errors 元素生物科学公司 2024-11-26 CN disclosed
US-20240167934-A1 EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH 2024-05-23 US disclosed
EP-4291870-A1 EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF Scintillon Institute for Biomedical and Bioenergy Research (US) 2023-12-20 EP disclosed
US-20230151407-A1 A METHOD FOR MULTIPLEXED DETECTION OF A PLURALITY OF TARGET BIOMOLECULES APLEX BIO AB (SE) 2023-05-18 US disclosed
WO-2022174056-A1 EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) 2022-08-18 WO disclosed