SCHEMBL29860168

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.57

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	4/20	0.57

▸	OPRD1	P41143	4/20	0.57

▸	GLP1R	P43220	13/20	0.54

▸	SCTR	P47872	1/20	0.54

▸	OPRK1	P41145	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29860251	0.96	OPRM1 (0.61)	OPRM1OPRD1GLP1RSCTROPRK1
SCHEMBL29616372	0.93	GLP1R (0.56)	OPRM1OPRD1GLP1RSCTROPRK1
SCHEMBL31243563	0.93	GLP1R (0.60)	GLP1R
SCHEMBL29375435	0.92	GLP1R (0.51)	OPRM1OPRD1GLP1RSCTROPRK1
SCHEMBL30432720	0.91	GLP1R (0.57)	GLP1RSCTR
SCHEMBL31741239	0.91	GLP1R (0.55)	GLP1RSCTR
SCHEMBL29394888	0.90	GLP1R (0.58)	GLP1RSCTR
SCHEMBL30184796	0.90	GLP1R (0.64)	GLP1RSCTR
SCHEMBL29462131	0.90	GLP1R (0.64)	GLP1RSCTR
SCHEMBL29372444	0.89	GLP1R (0.64)	GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4291647-A1	SUBTILISIN VARIANTS AND THEIR USE	Fresenius Kabi iPSUM S.r.l. (IT)	2023-12-20	—	—	EP	disclosed
WO-2022171667-A1	SUBTILISIN VARIANTS AND THEIR USE	Fresenius Kabi Ipsum S.R.L. (IT)	2022-08-18	—	—	WO	disclosed