SCHEMBL29375435

SCHEMBL29375435

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 14/20 0.51
SCTR P47872 1/20 0.50
OPRM1 P35372 3/20 0.48
OPRD1 P41143 3/20 0.48
OPRL1 P41146 1/20 0.48
OPRK1 P41145 1/20 0.47
GCGR P47871 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31740815 0.96 GLP1R (0.56) GLP1RSCTRGCGR
SCHEMBL31741239 0.94 GLP1R (0.55) GLP1RSCTRGCGR
SCHEMBL2465543 0.92 GLP1R (0.50) GLP1RSCTROPRM1OPRD1OPRL1
SCHEMBL29860168 0.92 OPRM1 (0.57) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL30635331 0.92 GLP1R (0.60) GLP1RSCTRGCGR
SCHEMBL29375282 0.90 GLP1R (0.56) GLP1RSCTR
SCHEMBL677186 0.90 GLP1R (0.45) GLP1RSCTROPRM1OPRD1OPRL1
SCHEMBL29616372 0.90 GLP1R (0.56) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL29376195 0.90 GLP1R (0.48) GLP1RSCTR
SCHEMBL31253154 0.90 GLP1R (0.45) GLP1RSCTROPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 CN disclosed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP GLP1R 1/4885SCTR 22/4885OPRM1 4009/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP GLP1R 1/4885SCTR 22/4885OPRM1 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.