SCHEMBL29861007

SCHEMBL29861007

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)OCc1ccccc1)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N(C)CC(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 0.46
CTSK P43235 5/20 0.45
CTSB P07858 3/20 0.45
CTSL P07711 2/20 0.45
CTSS P25774 2/20 0.45
CAPN1 P07384 2/20 0.42
CTSD P07339 3/20 0.41
CTSE P14091 3/20 0.41
HTRA1 Q92743 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30522071 0.96 BACE1 (0.44) BACE1CTSKCTSBCTSLCTSS
SCHEMBL31388662 0.94 BACE1 (0.47) BACE1CTSKCTSBCTSLCTSS
SCHEMBL30277766 0.91 CTSK (0.52) BACE1CTSKCTSBCTSLCTSS
SCHEMBL31388657 0.90 BACE1 (0.45) BACE1CTSKCTSBCTSLCTSS
SCHEMBL30522100 0.89 CTSK (0.54) BACE1CTSKCTSBCTSLCTSS
SCHEMBL29860969 0.86 CTSK (0.39) BACE1CTSKCTSBCTSLCTSS
SCHEMBL30522083 0.85 PSMB5 (0.45) BACE1CAPN1CTSDCTSE
SCHEMBL29860893 0.83 CTSK (0.38) BACE1CTSKCTSBCTSLCTSS
SCHEMBL31388652 0.83 CTSK (0.53) BACE1CTSKCTSBCTSLCTSS
SCHEMBL23893534 0.82 CAPN1 (0.48) CTSKCTSBCTSLCTSSCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331072-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-17 US disclosed
US-20250188116-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-12 US disclosed
CN-113056475-B Deprotection method for peptide compound or amide compound and resin removal method in solid phase reaction and method for producing peptide compound 中外制药株式会社 2024-09-24 CN disclosed
US-20230303619-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-28 US disclosed
US-11732002-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-08-22 US disclosed
CN-114867734-A Method for synthesizing peptide compound 中外制药株式会社 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732002-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound VIP, PEPD, MLN BACE1 1865/4885CTSK 423/4885CTSB 348/4885
US-12331072-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound VIP, PEPD, MLN BACE1 1865/4885CTSK 423/4885CTSB 348/4885
US-20230303619-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, PEPD, MLN BACE1 1865/4885CTSK 423/4885CTSB 348/4885
US-20250188116-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, PEPD, MLN BACE1 1865/4885CTSK 423/4885CTSB 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.