Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280148 | 0.81 | CDC7 (0.38) | DAODYRK1ADYRK1BAURKADAPK3 | |
| SCHEMBL22612785 | 0.80 | SIK2 (0.45) | DAOMAPK1DYRK1ADYRK1BPARG | |
| SCHEMBL31532055 | 0.80 | SIK2 (0.45) | DAOMAPK1DYRK1ADYRK1BPARG | |
| SCHEMBL29538008 | 0.79 | MEN1 (0.38) | DAOMAPK1NTRK1 | |
| SCHEMBL661610 | 0.79 | MEN1 (0.38) | DAOMAPK1NTRK1 | |
| SCHEMBL31290945 | 0.78 | PARG (0.35) | DAOMAPK1PARGTBK1 | |
| SCHEMBL23632980 | 0.76 | DYRK1A (0.35) | DYRK1ADYRK1B | |
| SCHEMBL31532076 | 0.76 | CDK4 (0.42) | MAPK1FGFR1CLK4 | |
| SCHEMBL31532117 | 0.76 | CDK4 (0.40) | DYRK1BAURKADAPK3PRKD3MAP4K4 | |
| SCHEMBL15280147 | 0.76 | PARG (0.32) | DAOMAPK1PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |