Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCND2 | P30279 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.40 |
| ▸ | CASP1 | P29466 | 11/20 | 0.40 |
| ▸ | CASP7 | P55210 | 11/20 | 0.40 |
| ▸ | GLA | P06280 | 9/20 | 0.40 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532055 | 0.83 | SIK2 (0.45) | MAPK1EGFRFGFR1 | |
| SCHEMBL22612785 | 0.83 | SIK2 (0.45) | MAPK1EGFRFGFR1 | |
| SCHEMBL31532117 | 0.79 | CDK4 (0.40) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL23632980 | 0.77 | DYRK1A (0.35) | HSD17B10MAT2A | |
| SCHEMBL29838035 | 0.77 | DYRK1A (0.35) | HSD17B10MAT2A | |
| SCHEMBL29861753 | 0.76 | PDK2 (0.39) | CLK4MAPK1FGFR1 | |
| SCHEMBL1899374 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP1A2CASP1CASP7 | |
| SCHEMBL31532080 | 0.75 | MAPK14 (0.47) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL255621 | 0.75 | MEN1 (0.46) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL15280148 | 0.74 | CDC7 (0.38) | ALDH1A1HSD17B10GLACLK4FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043349-A1 | PYRIMIDOPYRIDONE AND PTERIDONE DERIVATIVES AS INHIBITORS OF THE GCN2 KINASE, COMPOSITIONS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2025-03-06 | — | — | WO | disclosed |