SCHEMBL29862177

SCHEMBL29862177

CC(C)N(c1cccc2ccccc12)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.52
ALDH1A1 P00352 4/20 0.43
CYP2A6 P11509 2/20 0.43
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
STAT3 P40763 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
TDP1 Q9NUW8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23457994 1.00 SIGMAR1 (0.52) SIGMAR1ALDH1A1CYP2A6TUBB4ATUBB
SCHEMBL20887140 0.88 HPRT1 (0.52) SIGMAR1ALDH1A1CYP2A6TDP1TSHR
SCHEMBL11578431 0.83 SIGMAR1 (0.53) SIGMAR1ALDH1A1CYP2A6CYP1A2CYP2D6
SCHEMBL13338369 0.83 SIGMAR1 (0.52) SIGMAR1ALDH1A1CYP2A6TDP1TSHR
SCHEMBL29862152 0.81 SIGMAR1 (0.55) SIGMAR1ALDH1A1CYP2A6CYP1A2CYP2C19
SCHEMBL18387836 0.81 SIGMAR1 (0.55) SIGMAR1ALDH1A1CYP2A6CYP1A2CYP2C19
SCHEMBL11517103 0.77 SIGMAR1 (0.47) SIGMAR1ALDH1A1TDP1CYP1A2CYP2C19
SCHEMBL29851883 0.77 KDM4E (0.56) SIGMAR1ALDH1A1TDP1TSHRHSD17B10
SCHEMBL1509330 0.77 KDM4E (0.56) SIGMAR1ALDH1A1TDP1TSHRHSD17B10
SCHEMBL13338388 0.76 SIGMAR1 (0.49) SIGMAR1ALDH1A1CYP2A6CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069807-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS Sicpa Holding SA (CH) 2022-10-12 EP disclosed
EP-4069806-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON Sicpa Holding SA (CH) 2022-10-12 EP disclosed