SCHEMBL1509330

SCHEMBL1509330

CC(C)N(c1cccc2cccc(N(C(C)C)C(C)C)c12)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
GAA P10253 5/20 0.56
MAPT P10636 4/20 0.56
ALDH1A1 P00352 9/20 0.39
HSD17B10 Q99714 6/20 0.39
HPGD P15428 6/20 0.39
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HTR2A P28223 1/20 0.36
CES2 O00748 1/20 0.36
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36
MCL1 Q07820 1/20 0.36
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35
PABPC1 P11940 1/20 0.35
DNMT1 P26358 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29851883 1.00 KDM4E (0.56) KDM4EGAAMAPTALDH1A1HSD17B10
SCHEMBL1509281 0.93 KDM4E (0.48) KDM4EGAAMAPTALDH1A1HSD17B10
SCHEMBL1509297 0.80 KDM4E (0.35) KDM4EGAAMAPTELANE
SCHEMBL23457994 0.77 SIGMAR1 (0.52) MAPTALDH1A1HSD17B10HPGDTSHR
SCHEMBL29862177 0.77 SIGMAR1 (0.52) MAPTALDH1A1HSD17B10HPGDTSHR
SCHEMBL1509349 0.77 ELANE (0.36) KDM4EGAAMAPTELANE
SCHEMBL1509301 0.76 KDM4E (0.31) KDM4EGAAMAPTTSHRBCHE
SCHEMBL25760448 0.73 ALDH1A1 (0.42) KDM4EGAAMAPTALDH1A1HSD17B10
SCHEMBL28279 0.72 MAPT (1.00) KDM4EGAAMAPTALDH1A1HSD17B10
SCHEMBL6285846 0.72 MAPT (1.00) KDM4EGAAMAPTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4085085-A1 IMPROVED SHELF LIFE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2022-11-09 EP disclosed
US-11230566-B2 Shelf life mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2022-01-25 US disclosed
US-20210206789-A1 SHELF LIFE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-08 US disclosed
WO-2021138651-A1 IMPROVED SHELF LIFE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-08 WO disclosed
US-8361653-B2 Non-aqueous electrolyte secondary battery SHARP KABUSHIKI KAISHA (JP) 2013-01-29 US disclosed
US-20110052982-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY SHARP KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210206789-A1 SHELF LIFE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS FOXO3, MRTO4, RRP15 KDM4E 579/4885GAA 3508/4885MAPT 316/4885
US-11230566-B2 Shelf life mass polymerizable polycycloolefin compositions as optical materials FOXO3, MRTO4, RRP15 KDM4E 579/4885GAA 3508/4885MAPT 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.