Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834054 | 1.00 | USP30 (0.50) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL28952019 | 1.00 | USP30 (0.50) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL28834056 | 1.00 | USP30 (0.50) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL29862968 | 1.00 | USP30 (0.50) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL23360307 | 0.94 | ALDH1A1 (0.51) | BRD4PIM1PIM2GPR119POLB | |
| SCHEMBL28834189 | 0.93 | USP30 (0.52) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL28834190 | 0.93 | USP30 (0.52) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL28834375 | 0.93 | USP30 (0.52) | USP30PIK3CDBRD4PIM1PIM2 | |
| SCHEMBL29862513 | 0.86 | ALDH1A1 (0.52) | USP30BRD4BTKGPR119ALDH1A1 | |
| SCHEMBL1880284 | 0.86 | ALDH1A1 (0.52) | USP30BRD4BTKGPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |