SCHEMBL28834375

SCHEMBL28834375

CC(C)(C)OC(=O)N1CC[C@@H](Nc2ccnc3ccccc23)C1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 6/20 0.52
PIK3CD O00329 2/20 0.50
BTK Q06187 1/20 0.49
BRD4 O60885 1/20 0.48
PIK3CA P42336 1/20 0.46
GPR119 Q8TDV5 1/20 0.46
PIM1 P11309 2/20 0.46
PIM2 Q9P1W9 2/20 0.46
ALDH1A1 P00352 1/20 0.45
CNR1 P21554 2/20 0.45
IDO1 P14902 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28834190 1.00 USP30 (0.52) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL28834189 1.00 USP30 (0.52) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL29862513 0.94 ALDH1A1 (0.52) USP30BTKBRD4GPR119ALDH1A1
SCHEMBL1880284 0.94 ALDH1A1 (0.52) USP30BTKBRD4GPR119ALDH1A1
SCHEMBL28834054 0.93 USP30 (0.50) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL29862610 0.93 USP30 (0.50) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL28834056 0.93 USP30 (0.50) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL29862968 0.93 USP30 (0.50) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL28952019 0.93 USP30 (0.50) USP30PIK3CDBTKBRD4PIK3CA
SCHEMBL30958645 0.87 PIK3CD (0.52) USP30PIK3CDBRD4PIK3CAPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885PIK3CD 641/4885BTK 4379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.