Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21460268 | 1.00 | HTR6 (0.51) | HTR6HTR1AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL23360040 | 1.00 | HTR6 (0.51) | HTR6HTR1AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL29200505 | 0.90 | HTR6 (0.59) | HTR6HTR1AHTR2BSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7333915 | 0.89 | HTR6 (0.60) | HTR6HTR1AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL21460280 | 0.84 | ITK (0.42) | HTR6HTR1AHTR2BMAOBBRD4 | |
| SCHEMBL21460246 | 0.84 | PDK2 (0.43) | HTR6HTR1AHTR2BITKIDH2 | |
| SCHEMBL21460364 | 0.83 | PDK2 (0.42) | HTR6HTR1AHTR2BITKIDH2 | |
| SCHEMBL3313505 | 0.81 | PRKCZ (0.54) | ITK | |
| SCHEMBL3313511 | 0.81 | PRKCZ (0.54) | ITK | |
| SCHEMBL3319677 | 0.81 | PRKCZ (0.54) | ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |