SCHEMBL29862872

SCHEMBL29862872

CC(C)(C)OC(=O)N1CCC(Oc2nccc3ccccc23)CC1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.51
PIK3CD O00329 1/20 0.50
ACHE P22303 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5462197 1.00 GPR119 (0.51) GPR119PIK3CDACHE
SCHEMBL5474758 0.94 PIK3CD (0.57) PIK3CD
SCHEMBL16763551 0.87 PIK3CD (0.51) PIK3CD
SCHEMBL16763550 0.87 PIK3CD (0.51) PIK3CD
SCHEMBL23699085 0.84 CYP11B2 (0.46) GPR119PIK3CDACHE
SCHEMBL2800319 0.82 PIK3CD (0.59) GPR119PIK3CD
SCHEMBL16272021 0.82 GPR119 (0.53) GPR119ACHE
SCHEMBL5454387 0.81 GPR119 (0.57) GPR119
SCHEMBL4470775 0.81 GPR119 (0.51) GPR119PIK3CD
SCHEMBL21752528 0.81 GPR119 (0.55) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed