Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833973 | 1.00 | TACR1 (0.48) | TACR1CNR1USP30PIK3CDMET | |
| SCHEMBL28833974 | 1.00 | TACR1 (0.48) | TACR1CNR1USP30PIK3CDMET | |
| SCHEMBL29862440 | 1.00 | TACR1 (0.48) | TACR1CNR1USP30PIK3CDMET | |
| SCHEMBL28833985 | 1.00 | TACR1 (0.48) | TACR1CNR1USP30PIK3CDMET | |
| SCHEMBL29863261 | 0.89 | USP30 (0.47) | CNR1USP30PIK3CDBRD4BTK | |
| SCHEMBL28833993 | 0.89 | USP30 (0.47) | CNR1USP30PIK3CDBRD4BTK | |
| SCHEMBL29862687 | 0.89 | USP30 (0.47) | CNR1USP30PIK3CDBRD4BTK | |
| SCHEMBL28833994 | 0.89 | USP30 (0.47) | CNR1USP30PIK3CDBRD4BTK | |
| SCHEMBL28834141 | 0.89 | USP30 (0.47) | CNR1USP30PIK3CDBRD4BTK | |
| SCHEMBL23359881 | 0.87 | CRHR1 (0.41) | TACR1TRPV1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |