Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458203 | 1.00 | POLB (0.47) | POLBRAD52CA2NQO2RAB9A | |
| SCHEMBL23458107 | 0.84 | SMN1; SMN2 (0.53) | POLBRAD52ALDH1A1LMNAHPGD | |
| SCHEMBL24994173 | 0.81 | POLB (0.40) | POLBRAD52CA2RAB9AKDM4E | |
| SCHEMBL23485837 | 0.80 | POLB (0.41) | POLBRAD52NQO2RAB9AKDM4E | |
| SCHEMBL23486017 | 0.80 | POLB (0.39) | POLBRAD52CA2RAB9AKDM4E | |
| SCHEMBL23485985 | 0.74 | RAD52 (0.49) | POLBRAD52CA2NQO2RAB9A | |
| SCHEMBL23486012 | 0.73 | POLB (0.44) | POLBRAD52NQO2RAB9AKDM4E | |
| SCHEMBL23458134 | 0.72 | NQO2 (0.49) | POLBRAD52NQO2RAB9AKDM4E | |
| SCHEMBL23485838 | 0.72 | RAD52 (0.46) | POLBRAD52NQO2RAB9AKDM4E | |
| SCHEMBL21828697 | 0.70 | CA2 (0.46) | POLBCA2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069784-A1 | AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-10-12 | — | — | EP | disclosed |