Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23485838 | 0.83 | RAD52 (0.46) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL23458122 | 0.81 | HPGD (0.53) | RAD52POLBALDH1A1LMNAKMT2A | |
| SCHEMBL23485990 | 0.79 | RAD52 (0.43) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL29862950 | 0.74 | POLB (0.47) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL23458203 | 0.74 | POLB (0.47) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL23458134 | 0.74 | NQO2 (0.49) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL23486012 | 0.72 | POLB (0.44) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL23485837 | 0.69 | POLB (0.41) | RAD52POLBNQO2RAB9AKDM4E | |
| SCHEMBL5096192 | 0.68 | CA2 (0.59) | RAB9AKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL3359485 | 0.67 | POLB (1.00) | RAD52POLBRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110280-A1 | AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2021-06-10 | — | — | WO | disclosed |