Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803030 | 1.00 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLBNPC1 | |
| SCHEMBL7973371 | 0.90 | NOTUM (0.60) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL2842277 | 0.83 | NOTUM (0.48) | NOTUMNPC1RAB9AL3MBTL1 | |
| SCHEMBL2619231 | 0.81 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL6687673 | 0.81 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL4532424 | 0.81 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL3300297 | 0.81 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL24874051 | 0.80 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL5766165 | 0.80 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9 | |
| SCHEMBL1127318 | 0.80 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |