Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360685 | 1.00 | DYRK1A (0.53) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL5662572 | 0.92 | ROCK2 (0.58) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL29862650 | 0.92 | ROCK2 (0.58) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL23360441 | 0.88 | DYRK1A (0.54) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL528598 | 0.86 | ROCK2 (0.54) | ROCK2ROCK1 | |
| SCHEMBL659539 | 0.86 | ROCK2 (0.54) | ROCK2ROCK1 | |
| SCHEMBL23359964 | 0.82 | ALDH1A1 (0.51) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL30958681 | 0.82 | ALDH1A1 (0.51) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL23360200 | 0.82 | DYRK1A (0.50) | DYRK1ACCNA2CDK2GPR119ALDH1A1 | |
| SCHEMBL29862731 | 0.82 | DYRK1A (0.50) | DYRK1ACCNA2CDK2GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |