Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM6A | O15550 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23359872 | 1.00 | KMT2A (0.47) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL23360684 | 0.85 | KMT2A (0.48) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL23360445 | 0.82 | HPGD (0.58) | KMT2AMEN1ALDH1A1MAPTTP53 | |
| SCHEMBL1126280 | 0.81 | KMT2A (0.62) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL16861478 | 0.80 | KMT2A (0.51) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL20515237 | 0.80 | KDM4E (0.59) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL23360051 | 0.79 | KMT2A (0.53) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL15054071 | 0.79 | KDM4E (0.62) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL31056854 | 0.79 | KDM4E (0.62) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL29158845 | 0.79 | KMT2A (0.47) | KMT2AMEN1APAF1TDP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |