Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23359872 | 0.82 | KMT2A (0.47) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL29863233 | 0.82 | KMT2A (0.47) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL23360684 | 0.81 | KMT2A (0.48) | HPGDKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL15662242 | 0.80 | PSMD14 (0.50) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2143783 | 0.77 | EGLN1 (0.60) | HPGDKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL31026224 | 0.76 | EGLN1 (0.63) | HPGDKMT2AMEN1TP53MAPT | |
| SCHEMBL1126280 | 0.75 | KMT2A (0.62) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23360679 | 0.74 | PLAT (0.44) | HPGDKMT2AMAPTRPS6KB1KAT2B | |
| SCHEMBL3455022 | 0.74 | HPGD (1.00) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29862796 | 0.74 | RPS6KB1 (0.44) | HPGDKMT2AMAPTRPS6KB1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | HPGD 291/4885KMT2A 2822/4885MEN1 2004/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | HPGD 291/4885KMT2A 2822/4885MEN1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.