Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054071 | 1.00 | KDM4E (0.62) | KDM4EKMT2AMEN1MAP2K1TP53 | |
| SCHEMBL17113034 | 0.88 | KDM4E (0.71) | KDM4EKMT2AMEN1MAP2K1TP53 | |
| SCHEMBL17113200 | 0.88 | PSMD14 (0.56) | KDM4EKMT2AMEN1MAP2K1TP53 | |
| SCHEMBL28622697 | 0.86 | KDM4E (0.51) | KDM4EKMT2AMEN1MAP2K1TP53 | |
| SCHEMBL27872880 | 0.84 | KMT2A (0.46) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL31467097 | 0.84 | ELANE (0.49) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL26984289 | 0.84 | ELANE (0.49) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL21878477 | 0.83 | KDM4E (0.64) | KDM4EMAP2K1PSMD14ALDH1A1TDP1 | |
| SCHEMBL23360051 | 0.82 | KMT2A (0.53) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9945610 | 0.82 | KDM4E (0.64) | KDM4EKMT2AMEN1MAP2K1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |