Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98299 | 1.00 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6407953 | 0.89 | MAPT (0.53) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL20777507 | 0.86 | BCL2L1 (0.45) | PARP1BCL2L1BAD | |
| SCHEMBL3340538 | 0.82 | AHR (0.48) | PARP1CRBNHTR1AOPRK1AHR | |
| SCHEMBL30463280 | 0.82 | AHR (0.48) | PARP1CRBNHTR1AOPRK1AHR | |
| SCHEMBL15801195 | 0.81 | PNMT (0.45) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3593984 | 0.78 | NPC1 (0.52) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18885726 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2234486 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3212830 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789596-A | 2,6,10, 14-tetramethyl pentadecane derivative compound and preparation method and application thereof | 南京师范大学 | 2023-09-22 | — | — | CN | claimed |
| CN-114984055-A | Periplaneta americana intestinal bacteria metabolite extract, pharmaceutical composition and application of pharmaceutical composition in preparation of drugs for treating cardiovascular and cerebrovascular diseases | 天津中医药大学 | 2022-09-02 | — | — | CN | claimed |
| CN-116789596-B | 2,6,10, 14-Tetramethyl pentadecane derivative compound and preparation method and application thereof | Sida Times Pharmaceutical (Suzhou) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-116102537-B | Quinolinone derivative and preparation method and application thereof | 四川大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-116789596-A | 2,6,10, 14-tetramethyl pentadecane derivative compound and preparation method and application thereof | 南京师范大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116102537-A | Quinolinone derivative and preparation method and application thereof | 四川大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114984055-A | Periplaneta americana intestinal bacteria metabolite extract, pharmaceutical composition and application of pharmaceutical composition in preparation of drugs for treating cardiovascular and cerebrovascular diseases | 天津中医药大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |