Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29863302 | 1.00 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6407953 | 0.89 | MAPT (0.53) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL20777507 | 0.86 | BCL2L1 (0.45) | PARP1BCL2L1BAD | |
| SCHEMBL3340538 | 0.82 | AHR (0.48) | PARP1CRBNHTR1AOPRK1AHR | |
| SCHEMBL30463280 | 0.82 | AHR (0.48) | PARP1CRBNHTR1AOPRK1AHR | |
| SCHEMBL15801195 | 0.81 | PNMT (0.45) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3593984 | 0.78 | NPC1 (0.52) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18885726 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2234486 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3212830 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789596-A | 2,6,10, 14-tetramethyl pentadecane derivative compound and preparation method and application thereof | 南京师范大学 | 2023-09-22 | — | — | CN | claimed |
| CN-114984055-A | Periplaneta americana intestinal bacteria metabolite extract, pharmaceutical composition and application of pharmaceutical composition in preparation of drugs for treating cardiovascular and cerebrovascular diseases | 天津中医药大学 | 2022-09-02 | — | — | CN | claimed |
| CN-107337639-B | Stable carteolol hydrochloride, preparation method thereof and pharmaceutical composition for eyes | 深圳市瑞霖医药有限公司 | 2020-04-10 | — | — | CN | claimed |
| EP-0579096-B1 | A process for the preparation of 5-(3-tert.-butylamino-2-hydroxypropoxy)-3,4-dihydro- carbostyryl. | LUSOCHIMICA SPA (IT) | 1999-05-26 | — | — | EP | claimed |
| EP-0579096-A2 | A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl. | LUSOCHIMICA S.P.A. (IT) | 1994-01-19 | — | — | EP | claimed |
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | claimed |
| JP-55038364-A | — | — | None | — | — | JP | disclosed |
| JP-3077870-A | — | — | None | — | — | JP | disclosed |
| US-20260116891-A1 | Oxazepin Derivative | TEIJIN PHARMA LTD (JP) | 2026-04-30 | — | — | US | disclosed |
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | disclosed |
| EP-4512811-A1 | OXAZEPINE DERIVATIVE | Teijin Pharma Limited (JP) | 2025-02-26 | — | — | EP | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| WO-2023204308-A1 | OXAZEPINE DERIVATIVE | 帝人ファーマ株式会社 | 2023-10-26 | — | — | WO | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| EP-0011747-A1 | Aminopropanol derivatives of 6-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-ones, process for their preparation, and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-06-11 | — | — | EP | disclosed |
| JP-S5538364-A | BENZO IJ QUINOLIZINE-2-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | OTSUKA PHARMACEUT CO LTD | 1980-03-17 | — | — | JP | disclosed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |
| US-4081447-A | ADRENERGIC BLOCKING AGENTS | ABBOTT LABORATORIES (US) | 1978-03-28 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |
| US-4065456-A | CNS DEPRESSANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116891-A1 | Oxazepin Derivative | HCRTR2, HCRTR1, OXTR | NPC1 1107/4885MAPK13 2877/4885MAPK12 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.